SCHEMBL397044

SCHEMBL397044

C=C(Cc1ccc(S(=O)(=O)NCCCC)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.56
ALDH1A1 P00352 7/20 0.56
HTT P42858 5/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.51
TSHR P16473 2/20 0.47
TBXA2R P21731 1/20 0.47
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
MAPT P10636 2/20 0.45
POLB P06746 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45
EPHX2 P34913 1/20 0.44
GAA P10253 1/20 0.44
ALOX12 P18054 1/20 0.44
NAMPT P43490 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394859 0.92 CA12 (0.53) LMNAALDH1A1HTTKMT2AMEN1
SCHEMBL396597 0.86 ALDH1A1 (0.60) LMNAALDH1A1KMT2ASMN1; SMN2TSHR
SCHEMBL397008 0.85 ALDH1A1 (0.49) LMNAALDH1A1KMT2ASMN1; SMN2TSHR
SCHEMBL395695 0.80 SMN1; SMN2 (0.46) LMNAALDH1A1HTTSMN1; SMN2CA12
Methacrylic Acid SCHEMBL27492983 0.79 ALDH1A1 (0.61) LMNAALDH1A1HTTKMT2AMEN1
SCHEMBL398265 0.79 ALDH1A1 (0.49) LMNAALDH1A1SMN1; SMN2TSHRMAPT
SCHEMBL3701679 0.78 LMNA (0.63) LMNAALDH1A1HTTKMT2AMEN1
SCHEMBL5447486 0.77 TBXA2R (0.65) LMNAALDH1A1HTTKMT2AMEN1
SCHEMBL397724 0.76 AKR1C3 (0.48) ALDH1A1HTTKMT2ACA12CA9
SCHEMBL397450 0.76 CA12 (0.60) LMNAALDH1A1HTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed