Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | POLB | P06746 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | UBE2N | P61088 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.64 |
| ▸ | KRAS | P01116 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970958 | 1.00 | MAPT (0.68) | MAPTPOLBALDH1A1LMNAHPGD | |
| SCHEMBL14417610 | 1.00 | MAPT (0.68) | MAPTPOLBALDH1A1LMNAHPGD | |
| SCHEMBL28510034 | 0.86 | GAA (0.79) | MAPTPOLBALDH1A1LMNAMEN1 | |
| SCHEMBL28515982 | 0.84 | MAPT (0.79) | MAPTPOLBALDH1A1LMNAHPGD | |
| SCHEMBL28517632 | 0.80 | MAPT (0.62) | MAPTPOLBALDH1A1LMNAMEN1 | |
| SCHEMBL8299121 | 0.80 | KMT2A (0.66) | MAPTPOLBALDH1A1LMNAHPGD | |
| SCHEMBL13549787 | 0.78 | MAPT (0.73) | MAPTPOLBALDH1A1LMNAHPGD | |
| SCHEMBL12479231 | 0.78 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL28513870 | 0.77 | GAA (0.82) | MAPTPOLBALDH1A1LMNAHPGD | |
| SCHEMBL28521624 | 0.77 | MAPT (0.74) | MAPTPOLBALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541348-A | Hydrazone derivatives and use thereof | LINGUAGEN CORP (US) | 2009-09-23 | — | — | CN | claimed |
| US-20070207093-A1 | Hydrazone derivatives and uses thereof | LINQUAGEN CORP. | 2007-09-06 | — | — | US | claimed |
| CN-101541348-A | Hydrazone derivatives and use thereof | LINGUAGEN CORP (US) | 2009-09-23 | — | — | CN | disclosed |
| EP-1951215-A4 | HYDRAZONE DERIVATIVES AND USES THEREOF | REDPOINT BIO CORP (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1951215-A2 | HYDRAZONE DERIVATIVES AND USES THEREOF | Redpoint Bio Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| US-20070207093-A1 | Hydrazone derivatives and uses thereof | LINQUAGEN CORP. | 2007-09-06 | — | — | US | disclosed |
| WO-2007056159-A2 | HYDRAZONE DERIVATIVES AND USES THEREOF | REDPOINT BIO CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207093-A1 | Hydrazone derivatives and uses thereof | TAS2R1, TAS2R5, TAS1R1 | MAPT 4421/4885POLB 4551/4885ALDH1A1 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.