Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921978 | 0.85 | KDM4C (0.41) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL28133311 | 0.83 | MAPT (0.42) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5784920 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27571148 | 0.83 | MAPT (0.42) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL28841447 | 0.81 | ABCB11 (0.41) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27719512 | 0.81 | MAPT (0.41) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9358504 | 0.81 | LOXL2 (0.33) | ALDH1A1HTT | |
| SCHEMBL25984978 | 0.80 | KDM4C (0.44) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5725243 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL31680446 | 0.76 | MAPT (0.36) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |