Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27691342 | 0.83 | ANO1 (0.39) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| SCHEMBL25984978 | 0.81 | KDM4C (0.44) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| SCHEMBL28133311 | 0.81 | MAPT (0.42) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| SCHEMBL27571148 | 0.81 | MAPT (0.42) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| Hydrochloric Acid SCHEMBL27719512 | 0.79 | MAPT (0.41) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| Methyl Alcohol SCHEMBL28841447 | 0.79 | ABCB11 (0.41) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| SCHEMBL2921978 | 0.79 | KDM4C (0.41) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| SCHEMBL3971201 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAKDM4CMAPT | |
| SCHEMBL28494397 | 0.78 | RECQL (0.46) | ALDH1A1GAA | |
| SCHEMBL1936666 | 0.77 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396473-A | Imidazopyridinyl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112272553-B | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-112272553-A | Substituted benzofurans, benzopyrrole, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-110869360-A | Phenylacetamides as ROCK inhibitors | 百时美施贵宝公司 | 2020-03-06 | — | — | CN | disclosed |
| EP-1685125-B1 | Pyrrole derivatives useful for the treatment of proliferative diseases | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | disclosed |
| EP-1685125-A1 | PYRROL DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049603-A1 | PYRROL DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-06-02 | — | — | WO | disclosed |
| CN-1149085-C | Inhibition of RAF kinase with substituted heterocyclic ureas | — | 2004-05-12 | — | — | CN | disclosed |
| CN-1290164-A | Inhibition of RAF kinase with substituted heterocyclic ureas | BAYER AG (US) | 2001-04-04 | — | — | CN | disclosed |