Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.45 |
| ▸ | SCN2B | O60939 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.44 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972972 | 0.89 | MTNR1A (0.52) | PLA2G4A | |
| SCHEMBL13884091 | 0.83 | ABCB1 (0.47) | PLA2G4AABCB1METTL3METTL14 | |
| SCHEMBL4388023 | 0.82 | SCN2B (0.53) | KCNH2SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL13883750 | 0.81 | ABCB1 (0.42) | KCNH2SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL3969149 | 0.81 | MTNR1A (0.54) | PLA2G4ASCN9A | |
| Hydrochloric Acid SCHEMBL3969364 | 0.81 | MTNR1A (0.53) | PLA2G4ASCN9A | |
| SCHEMBL13883856 | 0.80 | MTNR1A (0.53) | PLA2G4A | |
| SCHEMBL3973159 | 0.79 | POLB (0.47) | — | |
| SCHEMBL3967405 | 0.76 | MTNR1A (0.55) | PLA2G4A | |
| SCHEMBL3972960 | 0.76 | ALDH1A1 (0.59) | KCNH2SCN2BSCN1ASCN1BSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |