Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | SCN2B | O60939 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972983 | 0.88 | FGFR1 (0.54) | ALDH1A1SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL4388023 | 0.85 | SCN2B (0.53) | ALDH1A1SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL142321 | 0.78 | DGAT2 (0.51) | ALDH1A1SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL12700552 | 0.77 | ALDH1A1 (0.62) | ALDH1A1SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL3968490 | 0.76 | POLB (0.53) | ALDH1A1KDM4EKMT2AMEN1ERN1 | |
| SCHEMBL3971220 | 0.76 | KCNH2 (0.47) | SCN2BSCN1ASCN1BSCN5ASCN9A | |
| SCHEMBL8418393 | 0.76 | ALDH1A1 (0.65) | ALDH1A1KCNH2 | |
| SCHEMBL20166497 | 0.76 | HSD17B10 (0.52) | ALDH1A1SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL13883667 | 0.75 | ALDH1A1 (0.51) | ALDH1A1SCN2BSCN1ASCN1BSCN5A | |
| SCHEMBL15970936 | 0.75 | MEN1 (0.44) | ALDH1A1KDM4EKMT2AMEN1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |