Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974184 | 0.93 | POLB (0.50) | POLBGAATSHRROCK1FGFR1 | |
| SCHEMBL3972972 | 0.85 | MTNR1A (0.52) | FGFR1MTNR1AMTNR1B | |
| SCHEMBL3968489 | 0.83 | POLB (0.47) | POLBGAATSHRROCK1FGFR1 | |
| SCHEMBL3976475 | 0.82 | PTAFR (0.45) | POLBGAATSHRMAPTHPGD | |
| SCHEMBL13883896 | 0.79 | POLB (0.38) | POLBGAATSHRROCK1KDM4E | |
| SCHEMBL13883862 | 0.79 | POLB (0.43) | POLBGAATSHRROCK1FGFR1 | |
| SCHEMBL3971220 | 0.79 | KCNH2 (0.47) | — | |
| SCHEMBL3968490 | 0.77 | POLB (0.53) | POLBGAATSHRFGFR1KDM4E | |
| SCHEMBL3969149 | 0.77 | MTNR1A (0.54) | FGFR1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3969364 | 0.76 | MTNR1A (0.53) | FGFR1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |