Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SCN2B | O60939 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971294 | 1.00 | FGFR1 (0.43) | FGFR1NR4A2CNR2SCN2BSCN1A | |
| SCHEMBL13883737 | 0.83 | FGFR1 (0.44) | FGFR1NR4A2CNR2SCN2BSCN1A | |
| SCHEMBL8450255 | 0.79 | HPGD (0.49) | HPGDKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3972983 | 0.78 | FGFR1 (0.54) | FGFR1NR4A2SCN2BSCN1ASCN1B | |
| SCHEMBL3973576 | 0.77 | MAPT (0.50) | FGFR1NR4A2SCN2BSCN1ASCN1B | |
| SCHEMBL13883742 | 0.77 | MAPT (0.50) | FGFR1NR4A2SCN2BSCN1ASCN1B | |
| SCHEMBL13883887 | 0.76 | MAPK8 (0.41) | FGFR1NR4A2KDM4ELMNAALDH1A1 | |
| SCHEMBL3975938 | 0.76 | MAPK8 (0.41) | FGFR1NR4A2KDM4ELMNAALDH1A1 | |
| SCHEMBL8733640 | 0.75 | MAOB (0.47) | HPGDLMNAALDH1A1MAPTPKM | |
| SCHEMBL3974115 | 0.71 | NR4A2 (0.63) | FGFR1NR4A2SCN2BSCN1ASCN1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |