Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SCN2B | O60939 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883742 | 1.00 | MAPT (0.50) | MAPTALDH1A1RAB9AFGFR1NR4A2 | |
| SCHEMBL13883738 | 0.85 | GAA (0.47) | MAPTALDH1A1RAB9AFGFR1PKM | |
| SCHEMBL3976474 | 0.85 | GAA (0.47) | MAPTALDH1A1RAB9AFGFR1PKM | |
| SCHEMBL3972983 | 0.84 | FGFR1 (0.54) | ALDH1A1FGFR1NR4A2SCN2BSCN1A | |
| SCHEMBL9428078 | 0.80 | ALDH1A1 (0.62) | MAPTALDH1A1RAB9ANR4A2PKM | |
| SCHEMBL9428072 | 0.80 | ALDH1A1 (0.62) | MAPTALDH1A1RAB9ANR4A2PKM | |
| SCHEMBL13883737 | 0.79 | FGFR1 (0.44) | MAPTALDH1A1FGFR1NR4A2PKM | |
| SCHEMBL3970192 | 0.77 | MTNR1A (0.51) | ALDH1A1FGFR1NR4A2LMNAPOLB | |
| SCHEMBL3971298 | 0.77 | FGFR1 (0.43) | MAPTALDH1A1FGFR1NR4A2PKM | |
| SCHEMBL3971294 | 0.77 | FGFR1 (0.43) | MAPTALDH1A1FGFR1NR4A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |