Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.63 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SCN2B | O60939 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972983 | 0.82 | FGFR1 (0.54) | NR4A2FGFR1ALDH1A1KDM4ELMNA | |
| SCHEMBL3967405 | 0.80 | MTNR1A (0.55) | NR4A2FGFR1NPC1MTNR1AMTNR1B | |
| SCHEMBL3970720 | 0.79 | PLA2G4A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL3969149 | 0.79 | MTNR1A (0.54) | NR4A2FGFR1SCN9AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL3969364 | 0.78 | MTNR1A (0.53) | NR4A2FGFR1SCN9AMTNR1AMTNR1B | |
| SCHEMBL408819 | 0.77 | NR4A2 (1.00) | NR4A2ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL13883856 | 0.77 | MTNR1A (0.53) | NR4A2FGFR1MTNR1AMTNR1B | |
| SCHEMBL3973576 | 0.77 | MAPT (0.50) | NR4A2FGFR1ALDH1A1KDM4ELMNA | |
| SCHEMBL3972972 | 0.77 | MTNR1A (0.52) | NR4A2FGFR1MTNR1AMTNR1B | |
| SCHEMBL13883742 | 0.77 | MAPT (0.50) | NR4A2FGFR1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |