Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10171075 | 0.89 | SIGMAR1 (0.41) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL10170022 | 0.89 | SIGMAR1 (0.41) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL10171077 | 0.89 | SIGMAR1 (0.41) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL10170018 | 0.86 | SIGMAR1 (0.38) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL25399165 | 0.78 | THRA (0.49) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL15285544 | 0.78 | EPHX1 (0.37) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL39346 | 0.78 | THRA (0.49) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL11351005 | 0.78 | THRA (0.49) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL39006 | 0.78 | THRA (0.49) | THRATHRBSIGMAR1ADH1A | |
| SCHEMBL11344593 | 0.78 | THRA (0.49) | THRATHRBSIGMAR1ADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079824-B2 | Method for the synthesis of an amino acetal | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-07-14 | — | — | US | disclosed |
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | US | disclosed |
| WO-2012005693-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | AOX1, DAO, ALDH7A1 | THRA 2508/4885THRB 3815/4885SIGMAR1 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.