SCHEMBL397221

SCHEMBL397221

C=C(C)C(=O)Nc1ccccc1S(=O)(=O)Nc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.51
CYP2C19 P33261 1/20 0.51
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
MAPT P10636 2/20 0.45
CCR8 P51685 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
GAA P10253 1/20 0.45
GFER P55789 1/20 0.45
SLC40A1 Q9NP59 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
POLB P06746 2/20 0.43
IDH1 O75874 2/20 0.42
PTK2B Q14289 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3824012 0.91 LMNA (0.46) CYP3A4CYP2C19ALDH1A1CA12CA9
SCHEMBL14394821 0.89 CA12 (0.51) ALDH1A1CA12CA9MAPTMEN1
SCHEMBL3824018 0.86 POLB (0.58) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL396099 0.84 SMN1; SMN2 (0.49) CYP2C19ALDH1A1KDM4EMAPTMEN1
SCHEMBL3250187 0.84 NPC1 (0.43) ALDH1A1KDM4ECA9SLC40A1TDP1
SCHEMBL3817707 0.83 SMN1; SMN2 (0.47) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL7596359 0.82 NPC1 (0.47) ALDH1A1KDM4ECA12CA9TDP1
SCHEMBL398489 0.81 SLC40A1 (0.52) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL393747 0.81 NPC1 (0.41) SLC40A1TDP1POLB
SCHEMBL11257019 0.81 NPC1 (0.41) ALDH1A1KDM4ECA9SLC40A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
EP-1048981-B1 Methode for negative type image recording FUJIFILM CORP (JP) 2009-08-19 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed
EP-1219464-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2008-02-13 EP disclosed
US-6068963-A CONTAINS (A) A POLYMER HAVING A HETEROCYCLIC GROUP CONTAINING AN UNSATURATED BOND THEREIN, (B) A CROSS-LINKING AGENT THAT CROSS-LINKS WITH THE AID OF AN ACID, AND (C) A COMPOUND THAT GENERATES AN ACID UPON EXPOSURE TO LIGHT OR HEAT. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
EP-0823659-B1 Negative type image recording material FUJI PHOTO FILM CO LTD (JP) 1999-12-01 EP disclosed
US-5948590-A CAPABLE OF PROCESSING DIRECTLY FROM COMPUTER AND OTHER DIGITAL DATA, WITH EXCELLENT PRINTING DURABILITY AT THE TIME OF PRINTING AND LACK OF STAINING. POLYMER, CURING AGENT, COMPOUND WHICH GENERATES AN ACID IN PRESENCE OF HEAT OR LIGHT. FUJI PHOTO FILM CO., LTD. (JP) 1999-09-07 US disclosed
EP-0854388-A2 Negative-type image recording materials FUJI PHOTO FILM CO., LTD. (JP) 1998-07-22 EP disclosed
EP-0823659-A1 Negative type image recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-02-11 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0330239-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-22 EP disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
EP-0330239-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 CYP3A4 1620/4885CYP2C19 2830/4885ALDH1A1 1302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.