Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976396 | 0.89 | ALDH1A1 (0.44) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3972011 | 0.82 | PRKCZ (0.57) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL12465762 | 0.80 | PRKCZ (0.47) | MEN1RAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3974360 | 0.80 | PRKCZ (0.62) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3972589 | 0.80 | PRKCZ (0.55) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3976107 | 0.79 | PRKCZ (0.58) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3980156 | 0.78 | PRKCZ (0.45) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3975200 | 0.76 | PRKCZ (0.48) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3974298 | 0.74 | PRKCZ (0.59) | ADORA1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3976906 | 0.74 | PRKCZ (0.55) | ADORA1MEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |