Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972248 | 0.89 | ADORA1 (0.49) | PRKCZMEN1KMT2AMAPTADORA1 | |
| SCHEMBL12465762 | 0.88 | PRKCZ (0.47) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3980970 | 0.81 | ALDH1A1 (0.65) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3976339 | 0.81 | PRKCZ (0.58) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3976253 | 0.77 | PRKCZ (0.50) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL689530 | 0.76 | PRKCZ (0.69) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3974317 | 0.75 | PRKCZ (0.54) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3981694 | 0.75 | PRKCZ (0.62) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3976107 | 0.75 | PRKCZ (0.58) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3974068 | 0.73 | CNR2 (0.51) | ALDH1A1PRKCZLMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |