Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5638797 | 0.98 | ALOX15 (0.67) | ALOX15PKMPARP10ALDH1A1RAB9A | |
| SCHEMBL2116281 | 0.90 | ALOX15 (0.54) | ALOX15PKMPARP10ALDH1A1MAPT | |
| SCHEMBL5637777 | 0.89 | ALOX15 (0.64) | ALOX15PKMPARP10ALDH1A1RECQL | |
| SCHEMBL809992 | 0.86 | ALOX15 (0.61) | ALOX15PKMALDH1A1MAPTKMT2A | |
| SCHEMBL22266179 | 0.85 | PARP10 (0.59) | ALOX15PKMPARP10ALDH1A1RAB9A | |
| SCHEMBL22266208 | 0.85 | PARP10 (0.59) | ALOX15PKMPARP10ALDH1A1RAB9A | |
| SCHEMBL22266215 | 0.85 | PARP10 (0.59) | ALOX15PKMPARP10ALDH1A1RAB9A | |
| SCHEMBL26383056 | 0.85 | PARP10 (0.59) | ALOX15PKMPARP10ALDH1A1RAB9A | |
| SCHEMBL12223524 | 0.85 | PKM (0.56) | ALOX15PKMPARP10ALDH1A1RECQL | |
| SCHEMBL5638782 | 0.85 | PKM (0.56) | ALOX15PKMPARP10ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051909-A1 | COMPOUNDS HAVING ACTIVITY IN CORRECTING MUTANT-CFTR CELLULAR PROCESSING AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-23 | — | — | WO | disclosed |