SCHEMBL809992

SCHEMBL809992

O=C(O)COCCOc1ccc(OCC(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.61
ALDH1A1 P00352 3/20 0.56
SMN1; SMN2 Q16637 1/20 0.55
FFAR1 O14842 1/20 0.55
PTPN7 P35236 2/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
KMT2A Q03164 1/20 0.53
PTPN12 Q05209 1/20 0.53
TBXAS1 P24557 1/20 0.50
PPARD Q03181 1/20 0.50
TSHR P16473 1/20 0.50
NR4A1 P22736 1/20 0.50
APEX1 P27695 1/20 0.50
PLA2G4B P0C869 4/20 0.49
PKM P14618 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2116281 0.96 ALOX15 (0.54) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL13418125 0.89 ALOX15 (0.53) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL5638797 0.88 ALOX15 (0.67) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL21418186 0.87 APP (0.53) ALOX15ALDH1A1SMN1; SMN2FFAR1TSHR
SCHEMBL25623896 0.87 MAPT (0.53) ALDH1A1SMN1; SMN2FFAR1MEN1MAPT
SCHEMBL3972378 0.86 ALOX15 (0.64) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL12703671 0.85 TAAR1 (0.46) ALOX15ALDH1A1SMN1; SMN2FFAR1PLA2G4B
SCHEMBL339492 0.85 ALOX15 (0.81) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL24897600 0.83 L3MBTL1 (0.60) ALDH1A1FFAR1MEN1KMT2APPARD
SCHEMBL12904680 0.83 PKM (0.57) ALOX15ALDH1A1FFAR1PTPN7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM DDT, ACMSD, HPD ALOX15 796/4885ALDH1A1 935/4885SMN1; SMN2 4695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.