SCHEMBL2116281

SCHEMBL2116281

O=C(O)COCCOc1ccc(OCCOCC(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.54
PKM P14618 1/20 0.52
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
FFAR1 O14842 1/20 0.48
PARP10 Q53GL7 1/20 0.48
PLA2G4B P0C869 3/20 0.47
RARB P10826 1/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
PTPN7 P35236 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN12 Q05209 1/20 0.47
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809992 0.96 ALOX15 (0.61) ALOX15PKMALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL5638797 0.92 ALOX15 (0.67) ALOX15PKMALDH1A1SMN1; SMN2FFAR1
SCHEMBL21418186 0.91 APP (0.53) ALOX15PKMALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL25623896 0.91 MAPT (0.53) ALDH1A1L3MBTL1SMN1; SMN2FFAR1MAPT
SCHEMBL3972378 0.90 ALOX15 (0.64) ALOX15PKMALDH1A1SMN1; SMN2FFAR1
SCHEMBL12703671 0.89 TAAR1 (0.46) ALOX15PKMALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL24897600 0.86 L3MBTL1 (0.60) ALDH1A1L3MBTL1FFAR1RARBMEN1
SCHEMBL12904680 0.86 PKM (0.57) ALOX15PKMALDH1A1L3MBTL1FFAR1
SCHEMBL3805601 0.85 ALOX15 (0.44) ALOX15PKMALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL13418125 0.85 ALOX15 (0.53) ALOX15ALDH1A1L3MBTL1SMN1; SMN2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-8802147-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 US disclosed
US-20140099370-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC (US) 2014-04-10 US disclosed
US-8552139-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL LLC (US) 2013-10-08 US disclosed
US-8552139-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL LLC (US) 2013-10-08 US disclosed
US-8552139-B2 Controlled release of biologically active compounds BEZWADA BIOMEDICAL LLC (US) 2013-10-08 US disclosed
US-20130142752-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC (US) 2013-06-06 US disclosed
US-20130142752-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC (US) 2013-06-06 US disclosed
US-20130142752-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC (US) 2013-06-06 US disclosed
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-8053591-B2 Functionalized biodegradable triclosan monomers and oligomers for controlled release BEZWADA BIOMEDICAL, LLC (US) 2011-11-08 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE BEZWADA BIOMEDICAL, LLC (US) 2009-04-23 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105352-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 ALOX15 468/4885PKM 2738/4885ALDH1A1 4403/4885
US-20130142752-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH ALOX15 551/4885PKM 1271/4885ALDH1A1 1816/4885
US-20120095114-A1 FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE LTN1, PARN, TLR3 ALOX15 468/4885PKM 2738/4885ALDH1A1 4403/4885
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH ALOX15 551/4885PKM 1271/4885ALDH1A1 1816/4885
US-20140099370-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH ALOX15 551/4885PKM 1271/4885ALDH1A1 1816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.