Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971633 | 0.84 | HDAC8 (0.54) | ERN1TUBB1HDAC8MAPTNPC1 | |
| SCHEMBL3970773 | 0.83 | BCHE (0.50) | ERN1BCHEMEN1KMT2AMAPT | |
| SCHEMBL13752645 | 0.81 | ALDH1A1 (0.41) | ERN1TUBB1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL21957648 | 0.77 | HDAC8 (0.54) | ERN1HDAC8MEN1KMT2APPARG | |
| SCHEMBL20815159 | 0.75 | TUBB1 (0.58) | ERN1TUBB1BCHEMEN1KMT2A | |
| SCHEMBL2573994 | 0.75 | TUBB1 (0.57) | ERN1TUBB1HDAC8NPC1RAB9A | |
| SCHEMBL5285862 | 0.74 | ERN1 (0.51) | ERN1TUBB1HDAC8MAPTNPC1 | |
| SCHEMBL13744497 | 0.74 | SMN1; SMN2 (0.51) | ERN1TUBB1HDAC8MAPTSMN1; SMN2 | |
| SCHEMBL31562251 | 0.73 | LIPE (0.49) | ERN1BCHEMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6958225 | 0.73 | ERN1 (0.50) | ERN1HDAC8BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | disclosed |
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | disclosed |
| WO-2009047791-A2 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | TLR4, TLR5, TLR1 | ERN1 2109/4885TUBB1 3314/4885HDAC8 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.