Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360692 | 0.81 | RAB9A (0.64) | RAB9AHCRTR2HTTTSHRALDH1A1 | |
| SCHEMBL4576862 | 0.81 | RAB9A (0.64) | RAB9AHCRTR2HTTTSHRALDH1A1 | |
| SCHEMBL7542669 | 0.81 | SMN1; SMN2 (0.45) | RAB9AHCRTR2XPNPEP1 | |
| SCHEMBL9978311 | 0.81 | RAB9A (0.56) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL23084663 | 0.80 | RAB9A (0.56) | RAB9AHCRTR2HTTTSHRALDH1A1 | |
| SCHEMBL4267780 | 0.80 | POLB (0.40) | RAB9AHCRTR2HTTALDH1A1GAA | |
| SCHEMBL10120835 | 0.79 | RAB9A (0.61) | RAB9AHCRTR2HTTTSHRALDH1A1 | |
| SCHEMBL2546757 | 0.78 | POLB (0.41) | RAB9AHCRTR2XPNPEP1 | |
| SCHEMBL2788731 | 0.78 | POLB (0.41) | RAB9AHCRTR2XPNPEP1 | |
| SCHEMBL793131 | 0.78 | POLB (0.41) | RAB9AHCRTR2XPNPEP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050159-A1 | COMBINATION OF FLUTICASONE FUROATE WITH 4- [ (4-CHL0R0PHENYL)METHYL] -2- ({ (2R)-I- [4-(4-{ [3-(HEXAHYDR0-LH-AZEPIN-L-YL) PROPYL ] OXY} PHENYL) BUTYL] -2-PYRROLIDINYL}METHYL) -1 (2H) - PHTHALAZ INONE | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |
| EP-2007735-A1 | 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS | Glaxo Group Limited (GB) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007122156-A9 | 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007122156-A1 | 2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |