Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13883738 | 0.86 | GAA (0.47) | POLBGAATSHRFGFR1ALOX15 | |
| SCHEMBL3976474 | 0.86 | GAA (0.47) | POLBGAATSHRFGFR1ALOX15 | |
| SCHEMBL3972983 | 0.82 | FGFR1 (0.54) | FGFR1KDM4EL3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL3974184 | 0.80 | POLB (0.50) | POLBGAATSHRFGFR1ALOX15 | |
| SCHEMBL5793272 | 0.79 | ALDH1A1 (0.55) | POLBHTTKDM4EL3MBTL1MAPT | |
| SCHEMBL3973159 | 0.77 | POLB (0.47) | POLBGAATSHRFGFR1ALOX15 | |
| SCHEMBL3968489 | 0.77 | POLB (0.47) | POLBGAATSHRFGFR1HTT | |
| SCHEMBL25431063 | 0.76 | POLB (0.66) | POLBGAATSHRFGFR1ALOX15 | |
| SCHEMBL3972960 | 0.76 | ALDH1A1 (0.59) | TSHRFGFR1HTTKDM4EMAPT | |
| SCHEMBL30158930 | 0.75 | FGFR1 (0.71) | POLBGAATSHRFGFR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |