Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975220 | 0.87 | PRKCZ (0.58) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2368746 | 0.86 | PRKCZ (0.58) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3975901 | 0.86 | ALDH1A1 (0.73) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3980970 | 0.85 | ALDH1A1 (0.65) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3976107 | 0.82 | PRKCZ (0.58) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3981694 | 0.82 | PRKCZ (0.62) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3995640 | 0.82 | ALDH1A1 (0.76) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3976339 | 0.82 | PRKCZ (0.58) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3974317 | 0.82 | PRKCZ (0.54) | PRKCZALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL136381 | 0.79 | ALDH1A1 (0.61) | PRKCZALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |