Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PRKCI | P41743 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979210 | 0.89 | MAPT (0.69) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL27729323 | 0.88 | ALDH1A1 (0.79) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3973230 | 0.86 | PRKCZ (0.60) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL5322173 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3980970 | 0.82 | ALDH1A1 (0.65) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3976445 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3976253 | 0.81 | PRKCZ (0.50) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3975112 | 0.81 | PRKCZ (0.50) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL689790 | 0.81 | ALDH1A1 (0.78) | ALDH1A1MAPTHSD17B10LMNAPRKCZ | |
| SCHEMBL3980569 | 0.78 | ADORA1 (0.61) | ALDH1A1MAPTHSD17B10LMNAPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |