Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.65 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974317 | 0.89 | PRKCZ (0.54) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL136381 | 0.89 | ALDH1A1 (0.61) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3976107 | 0.89 | PRKCZ (0.58) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3972011 | 0.89 | PRKCZ (0.57) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3976339 | 0.89 | PRKCZ (0.58) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3981694 | 0.89 | PRKCZ (0.62) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL1799330 | 0.86 | KMT2A (0.69) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL9720150 | 0.85 | ALDH1A1 (0.53) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3975112 | 0.85 | PRKCZ (0.50) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3976445 | 0.85 | ALDH1A1 (0.50) | ALDH1A1PRKCZLMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |