SCHEMBL3973317

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7670356	0.87	TAAR1 (0.33)	ESR1ESR2KIF11TSHRALDH1A1
	SCHEMBL27551686	0.80	ESR1 (0.52)	ESR1ESR2KIF11CYP3A4LMNA
	SCHEMBL24253164	0.78	ESR1 (0.50)	ESR1ESR2KIF11CYP3A4LMNA
	SCHEMBL7756496	0.78	ESR1 (0.50)	ESR1ESR2KIF11CYP3A4LMNA
	SCHEMBL13521454	0.77	ESR1 (0.58)	ESR1ESR2KIF11CYP3A4LMNA
	SCHEMBL3443841	0.77	ESR1 (0.48)	ESR1ESR2KIF11CYP3A4LMNA
	SCHEMBL6130604	0.76	ESR1 (0.54)	ESR1ESR2KIF11CYP3A4LMNA
	SCHEMBL10035138	0.75	TSHR (0.46)	KIF11TSHRSLC6A4NPC1CA1
	SCHEMBL15974610	0.75	CA1 (0.43)	SLC6A4ALDH1A1CA1CA2ALOX15
	SCHEMBL3948379	0.75	MGLL (0.61)	TSHRKDM4ECA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.