Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974573 | 0.91 | PTGDR2 (0.41) | PTGDR2MEN1KMT2A | |
| SCHEMBL3967751 | 0.84 | PTGDR2 (0.39) | PTGDR2MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL3965620 | 0.75 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL3968452 | 0.74 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL3969346 | 0.74 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2SLC34A1 | |
| SCHEMBL3968018 | 0.74 | PTGDR2 (0.39) | PTGDR2MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL3969315 | 0.74 | P2RX3 (0.36) | PTGDR2MAPK1MEN1KMT2AELANE | |
| SCHEMBL3968970 | 0.74 | PTGDR2 (0.46) | PTGDR2MEN1GAAKMT2AELANE | |
| SCHEMBL3969463 | 0.73 | PTGDR2 (0.47) | PTGDR2MEN1KMT2A | |
| SCHEMBL3970488 | 0.73 | SMN1; SMN2 (0.32) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |