SCHEMBL3973555

SCHEMBL3973555

Nc1cccc(S(=O)(=O)Nc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 1.00
HTR6 P50406 4/20 0.81
PKM P14618 4/20 0.73
KMT2A Q03164 4/20 0.66
KEAP1 Q14145 2/20 0.66
IL1RN P18510 1/20 0.66
ERAP1 Q9NZ08 1/20 0.66
PGR P06401 1/20 0.65
MEN1 O00255 2/20 0.61
ALDH1A1 P00352 1/20 0.61
PRMT1 Q99873 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
LMNA P02545 1/20 0.55
CA12 O43570 1/20 0.54
CA9 Q16790 1/20 0.54
MAPT P10636 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28271796 0.91 HTR6 (0.83) POLBHTR6PKMKMT2AKEAP1
SCHEMBL2723618 0.89 HTR6 (1.00) POLBHTR6PKMKMT2AKEAP1
Hydrochloric Acid SCHEMBL18953392 0.88 HTR6 (0.97) POLBHTR6PKMKMT2AKEAP1
SCHEMBL8081768 0.87 KEAP1 (0.79) POLBHTR6PKMKMT2AKEAP1
SCHEMBL25754843 0.85 PKM (1.00) POLBHTR6PKMKMT2AKEAP1
SCHEMBL14093757 0.85 POLB (0.73) POLBHTR6PKMKMT2AKEAP1
SCHEMBL7131571 0.85 POLB (0.73) POLBHTR6PKMKMT2AKEAP1
SCHEMBL28770134 0.85 POLB (0.73) POLBHTR6PKMKMT2AKEAP1
SCHEMBL10797719 0.83 POLB (0.71) POLBHTR6PKMKMT2AKEAP1
SCHEMBL1074934 0.83 POLB (0.70) POLBHTR6PKMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798167-A Preparation method of plant growth regulator and application of plant growth regulator in agriculture 贵州工业职业技术学院 2025-04-11 CN claimed
CN-112782301-A Method for accurately and quantitatively determining content of genotoxic impurity nitrite in medicine 上海微谱化工技术服务有限公司 2021-05-11 CN claimed
EP-1761541-B1 PYRRAZOLO-PYRIMIDINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2008-01-09 EP claimed
EP-1761541-A1 PYRRAZOLO-PYRIMIDINE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2007-03-14 EP claimed
WO-2005123738-A1 PYRRAZOLO-PYRIMIDINE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2005-12-29 WO claimed
CN-120172926-A Preparation method and application of active substance with disease resistance and plant growth regulation functions 贵州工业职业技术学院 2025-06-20 CN disclosed
CN-119798167-A Preparation method of plant growth regulator and application of plant growth regulator in agriculture 贵州工业职业技术学院 2025-04-11 CN disclosed
CN-119798167-A Preparation method of plant growth regulator and application of plant growth regulator in agriculture 贵州工业职业技术学院 2025-04-11 CN disclosed
WO-2024044757-A1 AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS Sanford Burnham Prebys Medical Discovery Institute (US) 2024-02-29 WO disclosed
US-20230242496-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-08-03 US disclosed
US-20230242496-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-08-03 US disclosed
WO-2021257544-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2021-12-23 WO disclosed
US-5424404-A Colorfastness, discoloration inhibition, red and yellow color; coloring paper, leather, printing on polymeric material BASF AKTIENGESELLSCHAFT (DE) 1995-06-13 US disclosed
EP-0482508-A1 Biscationic azo dyes and their intermediates BASF Aktiengesellschaft (DE) 1992-04-29 EP disclosed
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4289847-A 2-EQUIVALENT YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-09-15 US disclosed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US disclosed
US-4058517-A Preparation of a concentrated solution of an anionic azo dye containing a sulfonic acid group BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242496-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA BCL6, SOX18, BCL3 POLB 2630/4885HTR6 2375/4885PKM 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.