⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30372143 | 0.83 | CES2 (0.56) | — | |
| SCHEMBL24579382 | 0.80 | DAO (0.34) | — | |
| SCHEMBL21963324 | 0.79 | — | — | |
| SCHEMBL17201640 | 0.79 | CTPS1 (0.42) | — | |
| SCHEMBL28980662 | 0.76 | CES2 (0.34) | — | |
| SCHEMBL3625585 | 0.76 | ALAD (0.69) | — | |
| SCHEMBL16742614 | 0.74 | ALDH1A1 (0.45) | — | |
| SCHEMBL16742974 | 0.74 | HPGD (0.37) | — | |
| SCHEMBL71474 | 0.73 | DAO (0.58) | — | |
| SCHEMBL425130 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667054-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | Novartis AG (CH) | 2025-12-24 | — | — | EP | disclosed |
| CN-120398822-A | Process route for preparing 4-fluorothiophene-2-formate | 上海凌凯科技股份有限公司 | 2025-08-01 | — | — | CN | disclosed |
| CN-120398822-A | Process route for preparing 4-fluorothiophene-2-formate | 上海凌凯科技股份有限公司 | 2025-08-01 | — | — | CN | disclosed |
| EP-3880660-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2025-07-02 | — | — | EP | disclosed |
| CN-113166065-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2025-04-15 | — | — | CN | disclosed |
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| CN-116041415-B | Split-ring lupin alkane derivative, and preparation method and application thereof | 吉林农业大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-116041415-A | Split-ring lupin alkane derivative, and preparation method and application thereof | 吉林农业大学 | 2023-05-02 | — | — | CN | disclosed |
| US-20230031406-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-02 | — | — | US | disclosed |
| US-20230031406-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-02 | — | — | US | disclosed |
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20180282605-A1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2018-10-04 | — | — | US | disclosed |
| WO-2017060699-A1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-04-13 | — | — | WO | disclosed |
| WO-2009060030-A1 | HETEROARYL-SUBSTITUTED 2-PYRIDINYLMETHYLAMINE DERIVATIVES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058306-A1 | Heteroaryl-substituted 2-pyridinyl-methylamine derivatives | SCHWARZ PHARMA AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-7052742-B1 | Five membered-ring compounds and utilization thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2006-05-30 | — | — | US | disclosed |
| CN-1122333-A | Tetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 1996-05-15 | — | — | CN | disclosed |
| US-4097485-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4086241-A | Benzothiazolylimidazolidinone esters of furyl and thienyl substituted acids | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
| US-4061648-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |