Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 9/20 | 0.58 |
| ▸ | ALAD | P13716 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5350815 | 0.84 | DAO (0.57) | DAOALADGSK3BLCKFYN | |
| SCHEMBL5357129 | 0.84 | GSK3B (0.61) | DAOALADGSK3BHDAC3HDAC4 | |
| SCHEMBL9495737 | 0.83 | DAO (0.52) | DAOGSK3BTSHRCA12CA1 | |
| SCHEMBL7892513 | 0.81 | DAO (0.53) | DAOALADGSK3BTP53TSHR | |
| SCHEMBL7813005 | 0.79 | GSK3B (0.52) | DAOALADGSK3BHDAC4HDAC6 | |
| SCHEMBL7894090 | 0.79 | DAO (0.52) | DAOALADGSK3BHDAC3HDAC4 | |
| SCHEMBL12510152 | 0.79 | GSK3B (0.52) | DAOALADGSK3BHDAC3HDAC4 | |
| SCHEMBL10161068 | 0.79 | DAO (0.52) | DAOALADGSK3BHDAC3HDAC4 | |
| SCHEMBL2202050 | 0.79 | HDAC6 (0.55) | DAOALADGSK3BHDAC4HDAC1 | |
| SCHEMBL5357074 | 0.78 | DAO (0.50) | DAOALADGSK3BHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118879263-A | Polyurethane adhesive and preparation method thereof | 江苏百瑞特新材料有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-114716474-B | Quaternary phosphine ionic liquid and method for preparing 2, 5-furandicarboxylic acid polyester by catalysis of quaternary phosphine ionic liquid | 中国科学院大连化学物理研究所 | 2024-02-09 | — | — | CN | claimed |
| CN-115073838-B | Antibacterial plastic bottle cap and manufacturing process thereof | 宏全食品包装(清新)有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-113667136-B | Ultrahigh-stability and low-cost metal-organic framework material for efficiently separating acetylene/carbon dioxide and preparation method thereof | 浙江大学 | 2022-09-30 | — | — | CN | claimed |
| CN-115044026-A | Degradable high-barrier uvioresistant bio-based polyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2022-09-13 | — | — | CN | claimed |
| CN-114940748-A | High-heat-resistance high-barrier anti-ultraviolet bio-based copolyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2022-08-26 | — | — | CN | claimed |
| CN-114716474-A | Quaternary phosphine ionic liquid and method for preparing 2, 5-furandicarboxylic acid based polyester by catalyzing quaternary phosphine ionic liquid | 中国科学院大连化学物理研究所 | 2022-07-08 | — | — | CN | claimed |
| CN-113667136-A | Ultrahigh-stability and low-cost metal-organic framework material for efficiently separating acetylene/carbon dioxide and preparation method thereof | 浙江大学 | 2021-11-19 | — | — | CN | claimed |
| CN-110734542-B | Novel thiophene diformate copolyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2021-06-15 | — | — | CN | claimed |
| CN-110734542-A | novel thiophene diformate copolyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2020-01-31 | — | — | CN | claimed |
| US-8968711-B2 | Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process | L'OREAL (FR) | 2015-03-03 | — | — | US | claimed |
| US-8653048-B2 | Prodrugs based on gemcitabine structure and synthetic methods and applications thereof | SANLUGEN PHARMATECH LTD. (CN) | 2014-02-18 | — | — | US | claimed |
| CN-102428093-A | Prodrugs based on gemcitabine structure as well as synthetic method and application thereof | SANLUGEN PHARMATECH LTD | 2012-04-25 | — | — | CN | claimed |
| US-20120088908-A1 | Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof | SANLUGEN PHARMATECH LTD. (CN) | 2012-04-12 | — | — | US | claimed |
| EP-2423215-A1 | PRODRUGS BASED ON GEMCITABINE STRUCTURE AS WELL AS SYNTHETIC METHOD AND APPLICATION THEREOF | Sanlugen Pharmatech Ltd. (CN) | 2012-02-29 | — | — | EP | claimed |
| US-20100272660-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT | L'OREAL (FR) | 2010-10-28 | — | — | US | claimed |
| US-20100239509-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS | L'OREAL (FR) | 2010-09-23 | — | — | US | claimed |
| US-6924276-B2 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2005-08-02 | — | — | US | claimed |
| US-20030087924-A1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | SORENSON RODERICK JOSEPH (US) | 2003-05-08 | — | — | US | claimed |
| EP-1291345-A1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2003-03-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088908-A1 | Prodrugs Based on Gemcitabine Structure and Synthetic Methods and Applications Thereof | TYMP, DCTD, GLS2 | DAO 201/4885ALAD 1117/4885GSK3B 3953/4885 |
| US-20100239509-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS | CUTA, SUCLG1, KRT18 | DAO 758/4885ALAD 57/4885GSK3B 1948/4885 |
| US-20030087924-A1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | MMP13, MMP3, MMP9 | DAO 247/4885ALAD 1791/4885GSK3B 1715/4885 |
| US-20100272660-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT | ACMSD, CUTA, PCCA | DAO 1159/4885ALAD 29/4885GSK3B 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.