Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080669 | 0.86 | HSP90AA1 (0.34) | NUDT1HRH4CCNKCDK12HSP90AA1 | |
| SCHEMBL3973742 | 0.83 | DAO (0.34) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1148321 | 0.81 | HSP90AA1 (0.34) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1148697 | 0.79 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1344006 | 0.79 | HSP90AA1 (0.32) | HSP90AA1 | |
| SCHEMBL3973482 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1148442 | 0.76 | HSP90AA1 (0.35) | ALDH1A1MAPTHSD17B10HSP90AA1 | |
| SCHEMBL2596692 | 0.76 | HSP90AA1 (0.34) | GRIN2DGRIN1GRIN2AGRIN2BGRIN2C | |
| SCHEMBL1148410 | 0.73 | KDM4E (0.32) | KDM4EMAPTHPGDHSD17B10HSP90AA1 | |
| SCHEMBL1148636 | 0.73 | IDH1 (0.37) | KDM4EALDH1A1HPGDHSD17B10HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963366-A4 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | PROMEGA CORP (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1963366-A2 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | PROMEGA CORPORATION (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067557-A2 | METHODS FOR CYCLIC NUCLEOTIDE DETERMINATION | PROMEGA CORPORATION (US) | 2007-06-14 | — | — | WO | disclosed |
| EP-1583541-A2 | COMPOUNDS AND METHODS FOR INCREASING NEUROGENESIS | Neuronova AB (SE) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004045592-A2 | COMPOUNDS AND METHODS FOR INCREASING NEUROGENESIS | NEURONOVA AB (SE) | 2004-06-03 | — | — | WO | disclosed |