Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL740017 | 0.78 | MAPT (0.53) | ALDH1A1NPC1POLBRAB9AMAPT | |
| Hydrochloric Acid SCHEMBL31542018 | 0.78 | MAPT (0.53) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL29350099 | 0.75 | NPC1 (0.65) | ALDH1A1NPC1POLBRAB9APDGFRB | |
| SCHEMBL50667 | 0.75 | MAPT (0.56) | ALDH1A1NPC1POLBRAB9AMAPT | |
| SCHEMBL150476 | 0.75 | NPC1 (0.65) | ALDH1A1NPC1POLBRAB9APDGFRB | |
| SCHEMBL9394410 | 0.74 | ALDH1A1 (0.62) | ALDH1A1NPC1POLBRAB9APDGFRB | |
| SCHEMBL2386458 | 0.74 | ALDH1A1 (0.62) | ALDH1A1NPC1POLBRAB9APDGFRB | |
| SCHEMBL29524245 | 0.74 | ALDH1A1 (0.62) | ALDH1A1NPC1POLBRAB9APDGFRB | |
| SCHEMBL31242880 | 0.74 | ALDH1A1 (0.62) | ALDH1A1NPC1POLBRAB9APDGFRB | |
| SCHEMBL50867 | 0.73 | ALDH1A1 (0.61) | ALDH1A1NPC1POLBRAB9APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009047534-A2 | FUSED PHENOTHIAZINIUM COMPOUNDS, PREPARATION METHOD THEREOF AND USE AS PHOTOANTIMICROBIALS | PHARMALUCIA LTD (GB) | 2009-04-16 | — | — | WO | disclosed |