Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.43 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | NQO2 | P16083 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31542018 | 1.00 | MAPT (0.53) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL50667 | 0.97 | MAPT (0.56) | MAPTALDH1A1HPGDGLAACHE | |
| Iodide SCHEMBL1471059 | 0.94 | MAPT (0.53) | MAPTALDH1A1HPGDGLAACHE | |
| Water SCHEMBL1146714 | 0.92 | MAPT (0.50) | MAPTALDH1A1HPGDGLAACHE | |
| Iodide SCHEMBL1146708 | 0.90 | MAPT (0.48) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL3360974 | 0.84 | MAPT (0.42) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL8987972 | 0.82 | MAPT (0.40) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL12273001 | 0.79 | HTR3A (0.48) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL3973910 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDGLAACHE | |
| Iodide SCHEMBL12813166 | 0.77 | HTR3A (0.47) | MAPTALDH1A1HPGDGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240044833-A1 | ELECTROCHEMICAL BIOSENSOR FOR TARGET ANALYTE DETECTION | MCMASTER UNIVERSITY (CA) | 2024-02-08 | — | — | US | claimed |
| EP-4211259-A1 | ELECTROCHEMICAL BIOSENSOR FOR TARGET ANALYTE DETECTION | McMaster University (CA) | 2023-07-19 | — | — | EP | claimed |
| US-20220317082-A1 | DIFFERENTIAL SIGNAL BIOSENSING FOR DETECTING AN ANALYTE | MCMASTER UNIVERSITY (CA) | 2022-10-06 | — | — | US | claimed |
| WO-2022051872-A1 | ELECTROCHEMICAL BIOSENSOR FOR TARGET ANALYTE DETECTION | MCMASTER UNIVERSITY (CA) | 2022-03-17 | — | — | WO | claimed |
| EP-3942285-A1 | DIFFERENTIAL SIGNAL BIOSENSING FOR DETECTING AN ANALYTE | McMaster University (CA) | 2022-01-26 | — | — | EP | claimed |
| EP-4731795-A2 | SELECTIVE MULTIPLEXED ELECTROCHEMICAL PLATFORM FOR DETECTION OF HIV INFECTION | University of Maryland, Baltimore (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025231565-A1 | ELECTROCHEMICAL HYDROGEL MICRONEEDLE ARRAY BIOSENSORS | MCMASTER UNIVERSITY (CA) | 2025-11-13 | — | — | WO | disclosed |
| US-20250341518-A1 | MAGNETIC MICROGEL BEADS, METHODS OF MAKING AND USES THEREOF | UNIV MCMASTER (CA) | 2025-11-06 | — | — | US | disclosed |
| CN-119947729-A | Oral formulations of diaminophenothiazines and methods of making and using same in the treatment and/or prevention of disease | 罗颍诗 | 2025-05-06 | — | — | CN | disclosed |
| US-20250127794-A1 | THERAPEUTIC THIAZINE DYE COMPOSITIONS AND METHODS OF USE | AB BioInnovations, Inc. | 2025-04-24 | — | — | US | disclosed |
| WO-2025006598-A2 | SELECTIVE MULTIPLEXED ELECTROCHEMICAL PLATFORM FOR DETECTION OF HIV INFECTION | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2025-01-02 | — | — | WO | disclosed |
| US-20240044833-A1 | ELECTROCHEMICAL BIOSENSOR FOR TARGET ANALYTE DETECTION | MCMASTER UNIVERSITY (CA) | 2024-02-08 | — | — | US | disclosed |
| WO-2022150657-A1 | THERAPEUTIC THIAZINE DYE COMPOSITIONS AND METHODS OF USE | AB BioInnovations, Inc. (US) | 2022-07-14 | — | — | WO | disclosed |
| US-20220168317-A1 | Therapeutic Thiazine Dye Compositions and Methods of Use | AB BioInnovations, Inc. | 2022-06-02 | — | — | US | disclosed |
| WO-2022051872-A1 | ELECTROCHEMICAL BIOSENSOR FOR TARGET ANALYTE DETECTION | MCMASTER UNIVERSITY (CA) | 2022-03-17 | — | — | WO | disclosed |
| EP-3942285-A1 | DIFFERENTIAL SIGNAL BIOSENSING FOR DETECTING AN ANALYTE | McMaster University (CA) | 2022-01-26 | — | — | EP | disclosed |
| EP-1905861-B1 | METHOD FOR FORMATION OF ALUMINA COATING FILM, ALUMINA FIBER, AND GAS TREATMENT SYSTEM COMPRISING THE ALUMINA FIBER | K2R CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| EP-2430007-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | Wista Laboratories Ltd. (SG) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130977-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | WISTA LABORATORIES LTD. (SG) | 2010-11-18 | — | — | WO | disclosed |
| EP-1905861-A1 | METHOD FOR FORMATION OF ALUMINA COATING FILM, ALUMINA FIBER, AND GAS TREATMENT SYSTEM COMPRISING THE ALUMINA FIBER | K2R Co., Ltd. (JP) | 2008-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127794-A1 | THERAPEUTIC THIAZINE DYE COMPOSITIONS AND METHODS OF USE | THPO, IFNG, DPP4 | ACHE 2017/4885CHRM2 4846/4885CHRM1 4857/4885 |
| US-20220168317-A1 | Therapeutic Thiazine Dye Compositions and Methods of Use | THPO, DPP4, IFNG | ACHE 1891/4885CHRM2 4836/4885CHRM1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.