Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.43 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | NQO2 | P16083 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL740017 | 1.00 | MAPT (0.53) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL50667 | 0.97 | MAPT (0.56) | MAPTALDH1A1HPGDGLAACHE | |
| Iodide SCHEMBL1471059 | 0.94 | MAPT (0.53) | MAPTALDH1A1HPGDGLAACHE | |
| Water SCHEMBL1146714 | 0.92 | MAPT (0.50) | MAPTALDH1A1HPGDGLAACHE | |
| Iodide SCHEMBL1146708 | 0.90 | MAPT (0.48) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL3360974 | 0.84 | MAPT (0.42) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL8987972 | 0.82 | MAPT (0.40) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL12273001 | 0.79 | HTR3A (0.48) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL3973910 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDGLAACHE | |
| Iodide SCHEMBL12813166 | 0.77 | HTR3A (0.47) | MAPTALDH1A1HPGDGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3942285-B1 | DIFFERENTIAL SIGNAL BIOSENSING FOR DETECTING AN ANALYTE | UNIV MCMASTER (CA) | 2025-05-14 | — | — | EP | claimed |