Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912286 | 0.88 | F10 (0.60) | KDM4EPKMCCR3F10GPR119 | |
| SCHEMBL3900261 | 0.87 | F10 (0.55) | MGLLKDM4EPKMF10LMNA | |
| SCHEMBL3902517 | 0.84 | TGM2 (0.46) | F10GPR119MAPTPOLBNPC1 | |
| SCHEMBL3974111 | 0.84 | EPHX2 (0.49) | MGLLPKMF10GPR119NPC1 | |
| SCHEMBL3909028 | 0.82 | F10 (0.43) | MGLLKDM4EPKMF10MAPT | |
| SCHEMBL3249543 | 0.81 | MGLL (0.57) | MGLLGPR119SLC2A1 | |
| SCHEMBL6397967 | 0.80 | MGLL (0.64) | MGLLKDM4EPKMCCR3GPR119 | |
| SCHEMBL3911528 | 0.79 | RAB9A (0.50) | HDAC1F10MAPTPOLBNPC1 | |
| SCHEMBL3894603 | 0.79 | RORC (0.40) | MGLLKDM4EPKMHDAC1CCR3 | |
| SCHEMBL3894607 | 0.79 | RORC (0.40) | MGLLKDM4EPKMHDAC1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |