Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19883548 | 0.77 | CA12 (0.42) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL9537149 | 0.75 | DPP4 (0.41) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL9537159 | 0.75 | DPP4 (0.41) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL3974088 | 0.75 | AOC3 (0.40) | — | |
| Hydrochloric Acid SCHEMBL9439468 | 0.74 | DPP4 (0.40) | DPP4CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL9439130 | 0.74 | DPP4 (0.40) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL3972740 | 0.73 | CA12 (0.36) | CA12CA1CA2CA9 | |
| SCHEMBL3972397 | 0.73 | MC4R (0.53) | SLC7A5 | |
| SCHEMBL19981632 | 0.73 | CA12 (0.45) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL16246930 | 0.71 | CA12 (0.43) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-20060106256-A1 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106256-A1 | Substituted hydroxyethylamines | HNMT, PNMT, BCHE | DPP4 887/4885CA12 2360/4885CA1 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.