Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974113 | 0.73 | DPP4 (0.37) | CA12CA1CA2CA9 | |
| SCHEMBL2746432 | 0.72 | MAPT (0.38) | CA12CA1CA2CA9 | |
| SCHEMBL16246930 | 0.71 | CA12 (0.43) | CA12CA1CA2CA9MLYCD | |
| SCHEMBL16428936 | 0.70 | CA14 (0.47) | CA12CA1CA2CA9MLYCD | |
| SCHEMBL10135563 | 0.66 | CA14 (0.46) | — | |
| SCHEMBL10135562 | 0.66 | CA14 (0.46) | — | |
| SCHEMBL13223516 | 0.66 | MLYCD (0.40) | CA12CA1CA9MLYCD | |
| SCHEMBL27762530 | 0.66 | CA12 (0.38) | CA12CA1CA2CA9 | |
| SCHEMBL22386558 | 0.66 | CA14 (0.39) | MLYCD | |
| SCHEMBL1551622 | 0.65 | CYP1A2 (0.36) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-20060106256-A1 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106256-A1 | Substituted hydroxyethylamines | HNMT, PNMT, BCHE | CA12 2360/4885CA1 1188/4885CA2 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.