Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 20/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 13/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633293 | 0.77 | HSD17B10 (0.34) | — | |
| SCHEMBL4073531 | 0.77 | LMNA (0.39) | — | |
| SCHEMBL17165350 | 0.75 | PSEN1 (0.36) | S1PR3S1PR1 | |
| SCHEMBL19555328 | 0.75 | PSEN1 (0.36) | S1PR3S1PR1 | |
| SCHEMBL23628847 | 0.73 | LMNA (0.36) | — | |
| SCHEMBL15210905 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL17165355 | 0.70 | PSEN1 (0.38) | S1PR3S1PR1 | |
| SCHEMBL3973135 | 0.70 | PSEN1 (0.35) | S1PR3S1PR1 | |
| SCHEMBL20722071 | 0.70 | PSEN1 (0.35) | S1PR3S1PR1 | |
| SCHEMBL27753244 | 0.70 | APP (0.41) | S1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |