Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073531 | 0.95 | LMNA (0.39) | LMNASMN1; SMN2ALDH1A1ALPGHPGD | |
| SCHEMBL3633293 | 0.77 | HSD17B10 (0.34) | LMNAALDH1A1HPGDTDP1 | |
| SCHEMBL23628841 | 0.77 | TSHR (0.38) | LMNASMN1; SMN2ALDH1A1HPGDUSP2 | |
| SCHEMBL2494300 | 0.77 | KIF11 (0.37) | FFAR1MYCWDR5 | |
| SCHEMBL23628844 | 0.73 | DPP4 (0.37) | CTSLCTSSCTSK | |
| SCHEMBL3974300 | 0.73 | S1PR3 (0.35) | — | |
| SCHEMBL8053155 | 0.67 | LMNA (0.38) | LMNASMN1; SMN2ALDH1A1ALPGHPGD | |
| SCHEMBL2550741 | 0.67 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1ALPGHPGD | |
| SCHEMBL27032802 | 0.65 | BCL2L1 (0.44) | LMNASMN1; SMN2ALDH1A1ALPGFFAR1 | |
| SCHEMBL8487888 | 0.63 | ATM (0.43) | LMNASMN1; SMN2ALDH1A1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |