Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | PRKCZ | Q05513 | 9/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | PRKCI | P41743 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689305 | 0.86 | ALDH1A1 (0.70) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8290362 | 0.86 | PRKCZ (0.75) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8290366 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL689202 | 0.85 | PRKCZ (0.73) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL689612 | 0.84 | HSD17B10 (0.77) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8288638 | 0.84 | PRKCZ (0.72) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8288636 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL8289775 | 0.82 | ALDH1A1 (0.69) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL689025 | 0.82 | PRKCZ (0.73) | ALDH1A1MAPTMAPK1PRKCZHSD17B10 | |
| SCHEMBL12466271 | 0.82 | ADORA1 (0.49) | ALDH1A1MAPTPRKCZHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100732-A1 | RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS, COMPOSITION CONTAINING THEM AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2012-08-02 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |