SCHEMBL3976012

SCHEMBL3976012

Oc1ccc(C23CC4CC(C2)CC(c2ccc(O)cc2-c2ccc5ccccc5c2)(C4)C3)c(-c2ccc3ccccc3c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 8/20 0.43
ESR1 P03372 7/20 0.43
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
MIF P14174 1/20 0.40
CYP1A2 P05177 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
RARA P10276 1/20 0.39
MAPT P10636 1/20 0.39
RARB P10826 1/20 0.39
RARG P13631 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3971742 0.81 ESR2 (0.44) ESR2ESR1HSD17B1HSD17B2MIF
SCHEMBL4892810 0.74 ESR2 (0.54) ESR2ESR1HSD17B1HSD17B2MIF
SCHEMBL2008523 0.73 CYP1A2 (0.38) ESR2ESR1HSD17B1HSD17B2CYP1A2
SCHEMBL2426368 0.73 KMT2A (0.43) ESR1MEN1KMT2AALDH1A1RARB
SCHEMBL6454889 0.71 RARB (0.70) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL2004716 0.71 FAAH (0.37) ESR2ESR1HSD17B1HSD17B2CYP1A2
SCHEMBL2087563 0.70 CNR2 (0.43) ESR1MEN1KMT2AALDH1A1MAPT
SCHEMBL3749653 0.70 MEN1 (0.47) ESR1MEN1KMT2AKDM4EALDH1A1
SCHEMBL9456813 0.69 ESR2 (0.70) ESR2ESR1HSD17B1HSD17B2MIF
SCHEMBL632019 0.67 ESR2 (0.72) ESR2ESR1HSD17B1HSD17B2MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed