Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13716071 | 0.83 | ADRA2A (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL12348299 | 0.81 | HSD17B10 (0.36) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6370923 | 0.79 | ITGB3 (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL3875680 | 0.76 | PRSS1 (0.84) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL20090530 | 0.76 | APP (0.42) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL193570 | 0.75 | CES2 (0.44) | HDAC1 | |
| SCHEMBL771387 | 0.72 | LMNA (0.50) | MAPTGAAALDH1A1 | |
| SCHEMBL566487 | 0.72 | CES2 (0.46) | HDAC1 | |
| SCHEMBL320863 | 0.71 | PRSS1 (0.56) | PRSS1F2PRSS2PRSS3HDAC1 | |
| SCHEMBL22182052 | 0.71 | PRSS1 (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116236-A1 | Bisbenzamidine derivatives for use as antioxidant | Université de Mons-Hainaut (BE) | 2009-11-11 | — | — | EP | disclosed |