Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.56 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974445 | 0.88 | DRD2 (0.58) | DRD2DRD3ADRA1AHRH4DRD4 | |
| SCHEMBL13484955 | 0.87 | DRD3 (0.56) | DRD2DRD3ADRA1AHRH4DRD4 | |
| SCHEMBL3976405 | 0.86 | ALDH1A1 (0.49) | DRD2DRD3ADRA1AHRH4DRD4 | |
| SCHEMBL3973436 | 0.85 | DRD2 (0.58) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL8229460 | 0.85 | DRD2 (0.55) | DRD2DRD3ADRA1AHRH4DRD4 | |
| SCHEMBL3973175 | 0.84 | DRD3 (0.55) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL3976400 | 0.84 | ALDH1A1 (0.50) | DRD2DRD4MAPTTP53NPSR1 | |
| SCHEMBL3974264 | 0.83 | DRD3 (0.57) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL3984452 | 0.82 | DRD3 (0.62) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL8229500 | 0.82 | DRD2 (0.66) | DRD2DRD3ADRA1ADRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057138-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | Pierre Fabre Medicament (FR) | 2009-05-13 | — | — | EP | claimed |
| WO-2008009741-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | PIERRE FABRE MEDICAMENT (FR) | 2008-01-24 | — | — | WO | claimed |