Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884951 | 1.00 | CA1 (0.38) | CA1CA2CA12CA9MAOA | |
| SCHEMBL3975534 | 0.84 | SLC6A3 (0.40) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL13885334 | 0.84 | SLC6A3 (0.40) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL3976888 | 0.83 | L3MBTL1 (0.42) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL13884904 | 0.83 | L3MBTL1 (0.42) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL4090035 | 0.82 | MAPT (0.42) | MAOAMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13884895 | 0.82 | MAPT (0.42) | MAOAMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13884998 | 0.81 | FDPS (0.45) | TP53CYP3A4TSHRSMN1; SMN2CDK8 | |
| SCHEMBL13884897 | 0.80 | GAA (0.42) | CA1CA2MAPTGPR88 | |
| SCHEMBL15145999 | 0.80 | MAPT (0.50) | CA1CA2CA12CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |