Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884895 | 1.00 | MAPT (0.42) | MAPTFNTAFNTBALDH1A1TDP1 | |
| SCHEMBL13885334 | 0.84 | SLC6A3 (0.40) | MAPTALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL3975534 | 0.84 | SLC6A3 (0.40) | MAPTALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL13884998 | 0.84 | FDPS (0.45) | HTTSMN1; SMN2CYP2D6 | |
| SCHEMBL14511191 | 0.82 | MAPT (0.46) | MAPTFNTAFNTBALDH1A1TDP1 | |
| SCHEMBL13884904 | 0.82 | L3MBTL1 (0.42) | MAPTALDH1A1TDP1SMN1; SMN2CYP2D6 | |
| SCHEMBL3976888 | 0.82 | L3MBTL1 (0.42) | MAPTALDH1A1TDP1SMN1; SMN2CYP2D6 | |
| SCHEMBL3976412 | 0.82 | CA1 (0.38) | MAPTALDH1A1TDP1SMN1; SMN2MAOA | |
| SCHEMBL13884951 | 0.82 | CA1 (0.38) | MAPTALDH1A1TDP1SMN1; SMN2MAOA | |
| SCHEMBL13884897 | 0.80 | GAA (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |