SCHEMBL3976484

SCHEMBL3976484

Oc1ccc(C2(c3ccc(O)c(Cc4ccccc4)c3)C3CC4CC(C3)CC2C4)cc1Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48
BCL2 P10415 1/20 0.44
BCL2L1 Q07817 1/20 0.44
SLC7A5 Q01650 1/20 0.40
HSD11B1 P28845 4/20 0.40
ALOX5 P09917 1/20 0.40
IDH1 O75874 1/20 0.38
ALOX5AP P20292 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
HSP90AA1 P07900 1/20 0.35
KEAP1 Q14145 1/20 0.35
HNF4A P41235 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3975221 0.80 ESR1 (0.40) MEN1KMT2AHSD11B1POLBGAA
SCHEMBL3973988 0.80 MEN1 (0.48) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL3983497 0.77 ALOX5 (0.39) MEN1KMT2AHSD11B1ALOX5POLB
SCHEMBL3979579 0.76 GABRA1 (0.47) MEN1KMT2AHPGDHSD17B10HSD11B1
SCHEMBL3980599 0.75 BACE1 (0.44) MEN1KMT2AHPGDHSD17B10BCL2L1
SCHEMBL3754199 0.75 MEN1 (0.59) MEN1KMT2AHSD11B1ALOX5APPOLB
SCHEMBL3975098 0.75 TYR (0.40) MEN1KMT2ACYP3A4HPGDALOX15
SCHEMBL3975099 0.74 ALOX5 (0.40) MEN1KMT2ACYP3A4ALOX15BCL2L1
SCHEMBL3976002 0.71 MEN1 (0.42) MEN1KMT2AHSD17B10HSD11B1ALOX5AP
SCHEMBL1238135 0.71 ESR1 (0.50) MEN1KMT2AHSD11B1ALOX5APPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed