SCHEMBL3975221

SCHEMBL3975221

CCc1cc(C2(c3ccc(O)c(CC)c3)C3CC4CC(C3)CC2C4)ccc1O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
HSD11B1 P28845 10/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39
BACE1 P56817 2/20 0.38
HSD17B1 P14061 2/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
CTSD P07339 1/20 0.36
BACE2 Q9Y5Z0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3983497 0.88 ALOX5 (0.39) ESR1ESR2HSD11B1MEN1KMT2A
SCHEMBL3975098 0.85 TYR (0.40) ESR1ESR2HSD11B1MEN1KMT2A
SCHEMBL3975099 0.84 ALOX5 (0.40) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3979579 0.84 GABRA1 (0.47) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3980399 0.83 ALOX5 (0.42) HSD11B1MEN1KMT2A
SCHEMBL3977574 0.82 CYP1A2 (0.36) HSD11B1MEN1KMT2ABACE1CTSD
SCHEMBL3754199 0.80 MEN1 (0.59) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3976484 0.80 MEN1 (0.48) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3981612 0.79 GAA (0.45) MEN1KMT2APOLBGAAGFER
SCHEMBL1238135 0.79 ESR1 (0.50) ESR1ESR2HSD11B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101062975-B Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO 2012-05-30 CN disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed