SCHEMBL3983497

SCHEMBL3983497

CCCc1cc(C2(c3ccc(O)c(CCC)c3)C3CC4CC(C3)CC2C4)ccc1O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
HMGCR P04035 1/20 0.38
HSD11B1 P28845 11/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
GFER P55789 1/20 0.37
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
PRKCI P41743 1/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3975098 0.92 TYR (0.40) ALOX5HSD11B1MEN1KMT2APOLB
SCHEMBL3975099 0.90 ALOX5 (0.40) ALOX5HSD11B1MEN1KMT2APOLB
SCHEMBL3980399 0.89 ALOX5 (0.42) ALOX5HSD11B1MEN1KMT2A
SCHEMBL3975221 0.88 ESR1 (0.40) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3979579 0.81 GABRA1 (0.47) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3979935 0.78 MEN1 (0.50) ALOX5MEN1KMT2APOLBGAA
SCHEMBL3754199 0.77 MEN1 (0.59) HSD11B1MEN1KMT2APOLBGAA
SCHEMBL3976484 0.77 MEN1 (0.48) ALOX5HSD11B1MEN1KMT2APOLB
SCHEMBL3981612 0.77 GAA (0.45) MEN1KMT2APOLBGAAGFER
SCHEMBL1238135 0.76 ESR1 (0.50) HSD11B1MEN1KMT2APOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101062975-B Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO 2012-05-30 CN disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed