Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17324785 | 0.89 | CASP3 (0.70) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL19997207 | 0.87 | ALDH1A1 (0.60) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL26676568 | 0.85 | SLC26A4 (0.65) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL15897872 | 0.85 | MEN1 (0.60) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL26676637 | 0.85 | SLC26A4 (0.65) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL30664708 | 0.85 | SLC26A4 (0.65) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL24470655 | 0.84 | CASP3 (0.84) | SLC26A4KMT2AMEN1LMNABLM | |
| SCHEMBL26676529 | 0.84 | LMNA (0.65) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL26676598 | 0.84 | LMNA (0.65) | SLC26A4ALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL29713158 | 0.84 | CASP3 (0.84) | SLC26A4KMT2AMEN1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060030-A1 | HETEROARYL-SUBSTITUTED 2-PYRIDINYLMETHYLAMINE DERIVATIVES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058306-A1 | Heteroaryl-substituted 2-pyridinyl-methylamine derivatives | SCHWARZ PHARMA AG (DE) | 2009-05-13 | — | — | EP | disclosed |