Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 4/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097326 | 0.82 | CXCL8 (0.79) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL27354316 | 0.78 | CXCL8 (0.59) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL3289983 | 0.78 | CXCL8 (0.59) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL155982 | 0.78 | HSD17B10 (0.61) | CXCL8AKR1B1L3MBTL1MAPT | |
| SCHEMBL29431297 | 0.78 | HSD17B10 (0.61) | CXCL8AKR1B1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL2527513 | 0.77 | HSD17B10 (0.59) | CXCL8AKR1B1L3MBTL1MAPT | |
| SCHEMBL503961 | 0.77 | L3MBTL1 (0.77) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL3700349 | 0.77 | CXCL8 (0.57) | CXCL8AKR1B1CHRM1L3MBTL1TDP1 | |
| SCHEMBL28215186 | 0.77 | HSD17B10 (0.59) | CXCL8AKR1B1L3MBTL1MAPT | |
| SCHEMBL838629 | 0.77 | CAMK2A (0.68) | CXCL8AKR1B1CHRM1L3MBTL1CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2009058937-A2 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | AHR, MALT1, ABL1 | CXCL8 79/4885AKR1B1 589/4885CHRM1 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.