Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 5/20 | 0.35 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071677 | 0.84 | CYP4F2 (0.54) | L3MBTL1TDP1CYP4F2CYP4A11REN | |
| SCHEMBL3073300 | 0.84 | TTR (0.40) | L3MBTL1TDP1CYP4F2CYP4A11REN | |
| SCHEMBL3979694 | 0.82 | TSHR (0.41) | L3MBTL1TDP1RENBIRC5SLC6A4 | |
| SCHEMBL1039963 | 0.82 | REN (0.48) | L3MBTL1TDP1REN | |
| SCHEMBL3081718 | 0.82 | SLC6A4 (0.50) | L3MBTL1TDP1RENBIRC5SLC6A4 | |
| SCHEMBL7954853 | 0.81 | TAAR1 (0.42) | TDP1ALDH1A1 | |
| SCHEMBL3977128 | 0.81 | L3MBTL1 (0.43) | L3MBTL1TDP1CYP4F2CYP4A11REN | |
| SCHEMBL3239988 | 0.80 | PPARG (0.36) | L3MBTL1RENSLC6A4 | |
| SCHEMBL1596908 | 0.80 | KDM4E (0.43) | L3MBTL1TDP1SLC6A4KDM4EALDH1A1 | |
| SCHEMBL3077526 | 0.79 | BIRC5 (0.47) | L3MBTL1TDP1RENBIRC5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |