Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081718 | 0.83 | SLC6A4 (0.50) | MAPTTDP1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL3080203 | 0.83 | TSHR (0.44) | TSHRMAPTTDP1KMT2AKDM4E | |
| SCHEMBL3068255 | 0.83 | TSHR (0.41) | TSHRMAPTTDP1KMT2AKDM4E | |
| SCHEMBL1039963 | 0.83 | REN (0.48) | MAPTTDP1L3MBTL1SMN1; SMN2REN | |
| SCHEMBL3977294 | 0.82 | L3MBTL1 (0.39) | TDP1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL3977128 | 0.82 | L3MBTL1 (0.43) | MAPTTDP1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL7954853 | 0.82 | TAAR1 (0.42) | TSHRTDP1ALDH1A1TTRLMNA | |
| SCHEMBL4743467 | 0.81 | L3MBTL1 (0.41) | MAPTKDM4EL3MBTL1RENBIRC5 | |
| SCHEMBL3077526 | 0.81 | BIRC5 (0.47) | TSHRMAPTTDP1KMT2AL3MBTL1 | |
| SCHEMBL429553 | 0.79 | KDM4E (0.50) | TSHRMAPTTDP1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |